Active substances: Azithromycin
PID can result in tubal scarring that can lead to infertility and ectopic pregnancy. Annual screening for N. Additional risk factors for gonorrhea include inconsistent condom use among persons who are not in mutually monogamous relationships, previous or coexisting sexually transmitted infections, and exchanging sex for money or drugs.
Gonococcal infection, in particular, is concentrated in specific geographic locations and communities. Screening for gonorrhea in men and older women who are at low risk for infection is not recommended 108.
A recent travel history with sexual contacts outside of the United States should be part of any gonorrhea evaluation.
Diagnostic Considerations Specific microbiologic diagnosis of infection with N.
NAAT allows for the widest variety of FDA-cleared specimen types, including endocervical swabs, vaginal swabs, urethral swabs men, and urine from both men and women.
However, product inserts for each NAAT manufacturer must be carefully consulted because collection methods and specimen types vary. Culture is available for detection of rectal, oropharyngeal, and conjunctival gonococcal infection, but NAAT is not FDA-cleared for use with these specimens.
Some laboratories have met CLIA regulatory requirements and established performance specifications for using NAAT with rectal and oropharyngeal swab specimens that can inform clinical management. Certain NAATs that have been demonstrated to detect commensal Neisseria species might have comparable low specificity when testing oropharyngeal specimens for N gonorrhoeae 394.
In cases of suspected or documented treatment failure, clinicians should perform both culture and antimicrobial susceptibility testing because nonculture tests cannot provide antimicrobial susceptibility results.
Because N. Several non-nutritive swab transport systems are available that might maintain gonococcal viability for up to 48 hours in ambient temperatures 534-536.