Active substances: Norfloxacin
Patients taking any of these drugs concomitantly with norfloxacin should be carefully monitored.This includes any possible side effects. Do not pass it on to not listed in this leaflet.
Pregnancy Norfloxacin has been reported to rapidly cross the blood-placenta and blood-milk barrier, and is extensively distributed into the fetal tissues. For this reason norfloxacin and other fluoroquinolones are contraindicated during pregnancy due to the risk of spontaneous abortions and birth defects.
The manufacturer only recommends use of norfloxacin during pregnancy when benefit outweighs risk. Ciprofloxacin is being licensed for the treatment of Complicated Urinary Tract Infections and Pyelonephritis due to Escherichia coli and Inhalational Anthrax post-exposure and levofloxacin was recently licensed for the treatment of Inhalational Anthrax post-exposure.
However, the Fluoroquinolones are licensed to treat lower respiratory infections in children with cystic fibrosis in the UK. Adverse effects In general, fluoroquinolones are well tolerated, with most side-effects being mild to moderate.
The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients treated with other antibiotic classes.
Centers for Disease Control study found patients treated with fluoroquinolones experienced adverse events severe enough to lead to an emergency department visit more frequently than those treated with cephalosporins or macrolides, but less frequently than those treated with penicillins, clindamycin, sulfonamides, or vancomycin.
Among these, tendon problems and exacerbation of the symptoms of the neurological disorder myasthenia gravis are the subject of "black box" warnings in the United States.
Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients.
You should check with your doctor or pharmacist if you are not sure. The usual dose in adults is 1 film-coated tablet 400 mg norfloxacin twice daily. The recommended dose is 1 film-coated tablet 400 mg norfloxacin once daily. Swallow the tablets with a glass of water at least one hour before or two hours after a meal or drink of milk.
Preferably the tablets should be taken in the morning and evening. If you only take a single daily dose, always take this at the same time of day.
The duration of treatment depends on the type and severity of infection. For women with acute, uncomplicated inflammation of the bladder, the usual duration of treatment is a 3 day course of this medicine with the recommended dose.
In the treatment of urinary tract infections, adults will generally need to use this medicine for 7-10 days. In chronic inflammation of the prostate the usual duration of treatment is 4 weeks.
The symptoms of urinary tract infection, such as a burning sensation experienced during passing water, pain, and fever, will generally disappear within 1-2 days.
However, the treatment course with this medicine should be continued for up to 12 weeks in chronic relapsing urinary tract infections.
If you take more Norfloxacin 400 mg than you should If you have taken a double dose, you only need to contact your doctor if side effects occur.
Continue taking your medicine regularly as prescribed. If you have taken more than a double dose by mistake, contact your doctor immediately.
If you forget to take Norfloxacin 400 mg Do not take a double dose to make up for a forgotten tablet, just carry on with the next one as normal. If you stop taking Norfloxacin 400 mg It is important that you complete the course of treatment, even if you begin to feel better after a few days.
If you have any further questions on the use of this product, ask your doctor or pharmacist or nurse. Like all medicines, this medicine can cause side effects, although not everybody gets them.