Active substances: Norfloxacin
Duration of therapy should be determined on an individual basis but is typically 10 to 14 days. Selected guidelines for the management of recurrent complicated UTIs are listed in Table 5.
Guidelines for the Management of Recurrent Complicated UT Is A single urine specimen with a quantitative count of at least 10 5 colony-forming units per mL is consistent with a diagnosis of UTI in asymptomatic patients.
If clinically feasible, initiation of antimicrobial therapy should be delayed until urine culture results are available. Parenteral antimicrobial therapy is indicated if patients are unable to tolerate oral therapy, have impaired gastrointestinal absorption, have hemodynamic instability, or if the infecting organism is known or suspected to be resistant to oral agents.
The duration of therapy should be seven days for patients with lower urinary tract symptoms, and 10 to 14 days for patients with upper urinary tract symptoms or sepsis syndrome. Patients with chronic use of urologic devices should receive the shortest possible duration of therapy to limit antimicrobial pressure leading to resistance.
This can happen during treatment or up to several months after you stop taking ofloxacin.
Tell your doctor if you have ever had: tendon problems, bone problems, arthritis, or other joint problems; blood circulation problems, aneurysm, narrowing or hardening of the arteries; heart problems, high blood pressure; a genetic disease such as Marfan syndrome or Ehler's-Danlos syndrome; diabetes; a muscle or nerve disorder, such as myasthenia gravis; liver or kidney disease; long QT syndrome in you or a family member; or low levels of potassium in your blood hypokalemia.
Ofloxacin is not approved for use by anyone younger than 18 years old.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
You should not breast-feed while using this medicine. How should I take ofloxacin?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take ofloxacin with water, and drink extra fluids to keep your kidneys working properly.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.
Skipping doses can increase your risk of infection that is resistant to medication.
Ofloxacin will not treat a viral infection such as the flu or a common cold. Do not share ofloxacin with another person.