Active substances: Amoxicillin
In the same group 5 dogs presented blunted, and one dog fused villi. In RIF group, 4 dogs showed mild, 7 moderate, and 4 severe inflammation.
In this group, 8 dogs showed blunted, and 2 fused villi.
The present study was aimed to compare the clinical efficacy of rifaximin, a non-absorbable rifamycin, with respect to metronidazole, an antibiotic commonly prescribed against canine IBD, in dogs in which non-hypoproteinemic chronic enteropathy was diagnosed.
There was, however, no significant difference in efficacy between metronidazole and rifaximin, which demonstrated to be equally effective in this clinical trial. However, since CRP is a non-specific marker of inflammation, the interpretation of this result should be prudently considered without further studies.
Whereas many studies have shown that an alteration of gut microbiota takes place in dogs and cats with chronic intestinal inflammation, and that this dysbiosis is similar to those observed in human IBD or in animal models of intestinal inflammation, the composition of such abnormal bacteria population seems to be variable, thus making the choice of a selective antibiotic treatment a very difficult task.
In the present study, rifaximin, a broad spectrum antibiotic, was effective as metronidazole, whose activity is directed only against anaerobes. This result seems to suggest that anaerobic bacteria could be particularly important in the pathogenesis of chronic diarrhoea in dogs; as a matter of fact, a recent study evidenced an increased number of anaerobic species in the mucosa of dogs with chronic enteropathies.
By contrast, other studies conducted in dogs with IBD, found either a reduction of anaerobic bacteria or no significant alterations compared to healthy subjects. Interestingly, it was observed that rifaximin was able to enhance the growth of beneficial bacteria such as Bifidobacteria or Faecalibacterium praunsnitzii, and that a reduced population of Faecalibacterium in particular, which seems to exert a protective activity against intestinal inflammation, is usually present in human patients and dogs with IBD.
The cycling was designed to simulate three conditions: below critical pH of enamel hydroxyapatite pH 5. The samples were analyzed by scanning electron microscopy SEM, Fourier infrared spectroscopy FTIR and solutions were quantified fluoride specific ion electrode and phosphate colorimetric method.
At pH 4. It is concluded that the irradiated fluorapatite has critical dissolution pH different from fluorapatite formed only with the application of fluorine.
Several types of lasers offer new technical modalities for the decontamination of periodontal pockets and root surfaces in nonsurgical treatment for effective ablation and strong bactericidal and detoxificative effects.
Nd: YAG can eradicate periopathogens and can cause significantly higher reduction of the gingival index, probing pocket depth and clinical attachment level when used as an adjunct to conventional debridement.
Er: YAG laser removes deposits and biofilm thoroughly, creating biocompatible surfaces more conducive for reattachment than those obtained with conventional methods and can be effectively used to reduce the number of bacteria residing in biofilms.
The concept of periodontal laser treatment is based on reducing bacterial penetration in the infected periodontal pocket.
Results: 6 patients 5 females and 1 using a multidiodic laser Lumix C.